ADNP Antibody (6B8) Summary

jc.2015-2690

ADNP Antibody (6B8) Summary

    Immunogen
    ADNP (NP_056154, 1018 a.a. ~ 1103 a.a) partial recombinant protein with GST tag. TMQGDREQLKWKNSSYGKVEGFWSKDQSQWKNASENDERLSNPQIEWQNSTIDSEDGEQFDNMTDGVAEPMHGSLAGVKLSSQQA
    Localization
    Nuclear
    Specificity
    ADNP – activity-dependent neuroprotector
    Isotype
    IgG3 Kappa
    Clonality
    Monoclonal
    Host
    Mouse
    Gene
    ADNP
    Purity
    IgG purified
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Applications/Dilutions

    Dilutions
        Western Blot 1:500
        ELISA
    Application Notes
    Antibody Reactive against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

    Storage
    Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
    Buffer
    Phosphate buffered saline, pH 7.4
    Preservative
    No Preservative
    Purity
    IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for ADNP Antibody (6B8)

      Activity-dependent neuroprotective protein
      activity-dependent neuroprotector homeobox
      activity-dependent neuroprotector
      ADNP homeobox 1
      ADNP
      ADNP1
      ADNP1KIAA0784activity-dependent neuroprotector homeobox protein

Background

Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

product targets : PI4K_Akt_mTOR inhibitors