srep17144

ADAM12 Antibody Summary

    Immunogen
    ADAM12 (NP_003465, 208 a.a. – 304 a.a.) partial recombinant protein with GST tag. ETLKATKYVELVIVADNREFQRQGKDLEKVKQRLIEIANHVDKFYRPLNIRIVLVGVEVWNDMDKCSVSQDPFTSLHEFLDWRKMKLLPRKSHDNAQ
    Specificity
    ADAM12 – a disintegrin and metalloproteinase domain 12 (meltrin alpha)
    Isotype
    IgG
    Clonality
    Polyclonal
    Host
    Mouse
    Gene
    ADAM12
    Purity
    Unpurified
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Applications/Dilutions

    Dilutions
        Western Blot
        ELISA
    Application Notes
    The quality control of this antibody is limited to WB on the immunizing protein. It has been used for ELISA. Abnovas recommended working dilutions for western analysis are as follows: 1:500 dilution for ascites 1:1000 for purified Ig 1:500

Packaging, Storage & Formulations

    Storage
    Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
    Buffer
    Whole antisera with 50% Glycerol
    Preservative
    No Preservative
    Purity
    Unpurified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for ADAM12 Antibody

      a disintegrin and metalloproteinase domain 12 (meltrin alpha)
      ADAM 12
      ADAM metallopeptidase domain 12
      ADAM12
      disintegrin and metalloproteinase domain-containing protein 12
      EC 3.4.24
      EC 3.4.24.58
      MCMP
      MCMPMltna
      Meltrin alpha
      meltrin-alpha
      MLTNA
      MLTNEC 3.4.24.-

Background

This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene has two alternatively spliced transcripts: a shorter secreted form and a longer membrane-bound form. The shorter form is found to stimulate myogenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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