ACE/CD143 Antibody (RM0069-9B21) Summary
Mouse recombinant ACE protein
This was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with mouse recombinant Angiotensin-Converting Enzyme (ACE, CD143) protein
IgG2
Monoclonal
Rat
ACE
Protein G purified
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Applications/Dilutions
- Western Blot 1:500-1:1000
This antibody detects mouse 4-1BB in Western blots.
Reactivity Notes
Mouse.
Packaging, Storage & Formulations
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
A 0.2 um filtered solution in PBS
No Preservative
LYOPH
Protein G purified
Reconstitute with 0.2 ml sterilized PBS to a final concentration of 0.5 mg/ml.
Alternate Names for ACE/CD143 Antibody (RM0069-9B21)
- ACE
- ACE1angiotensin converting enzyme, somatic isoform
- angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
- carboxycathepsin
- CD143 antigen
- CD143
- DCP
- DCP1
- DCP1angiotensin-converting enzyme
- dipeptidyl carboxypeptidase 1
- Dipeptidyl carboxypeptidase I
- EC 3.2.1.-
- EC 3.4.15.1
- Kininase II
- MGC26566
- MVCD3
- peptidase P
- testicular ECA
Background
ACE converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilatator. ACE exists in two forms, a 170KD somatic form and a 90KD germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.