oncotarget.6525

5-HT7 Antibody Summary

    Immunogen
    Synthetic 19 amino acid peptide from 3rd cytoplasmic domain of human 5HT7 Receptor.
    Epitope
    3rd cytoplasmic domain of human
    Specificity
    Human 5HT7 Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
    Predicted Species
    Rat (95%), Porcine (95%), Guinea Pig (95%), Bovine (95%), Hamster (95%), Canine (95%), Monkey (100%), Primate (95%), Equine (95%). Backed by our 100% Guarantee.
    Isotype
    IgG
    Clonality
    Polyclonal
    Host
    Rabbit
    Gene
    HTR7
    Purity
    Immunogen affinity purified
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Applications/Dilutions

    Dilutions
        ELISA 1:100 – 1:2000
        Immunohistochemistry-Paraffin 10 ug/ml
    Positive Control 5-HT7 Lysate (NBL1-11783)

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Panda (100%), Mouse (89%), Bat (89%), Opossum (84%).

Packaging, Storage & Formulations

    Storage
    Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
    Buffer
    PBS
    Preservative
    0.1% Sodium Azide
    Concentration
    1.0 mg/ml
    Purity
    Immunogen affinity purified

Alternate Names for 5-HT7 Antibody

      5HT7
      5-HT7
      5-HT-7
      5-HT75-hydroxytryptamine receptor 7
      5-HT-X
      5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)
      HTR7
      serotonin 5-HT-7 receptor
      Serotonin receptor 7

Background

The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

CMX002

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